PDGFRα-Expressing Mesenchyme Regulates Thymus Growth And The Availability Of Intrathymic Niches
نویسندگان
چکیده
Correspondence should be addressed to G. Anderson Address: MRC Centre for Immune Regulation, Institute for Biomedical Research, Birmingham University Medical School, Birmingham B15 2TT, UK Tel: 0044-121-414 6817 FAX: 0044-121-464-3599 Email: [email protected] Words of abstract: 200 Word of text: 4,025 Scientific heading: HAEMATOPOIESIS Blood First Edition Paper, prepublished online September 28, 2006; DOI 10.1182/blood-2006-05-023143
منابع مشابه
PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches.
The thymus provides a specialized site for the production of T cells capable of recognizing foreign antigens in the context of self-major histocompatibility complex (MHC) molecules. During development, the thymus arises from an epithelial rudiment containing bipotent progenitors that differentiate into distinct cortical and medullary epithelial cells to regulate the maturation and selection of ...
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